Immunopathology of Lung Disease

Severe Murine Lung Immunopathology

Immunopathology of Chagas disease.

The main clinical forms of Chagas disease (acute, indeterminate and chronic cardiac) present strong evidences for the participation of the immune system on pathogenesis. Although parasite multiplication is evident during acute infection, the intense acute myocarditis of this phase exhibits clear ultrastructural signs of cell-mediated immune damage, inflicted to parasitized and non-parasitized m...

Immunopathology of Beh9et's disease

Behqet's disease (BD) is best considered as a systemic vasculitis in which recurrent orogenital ulceration is a prominent feature. In 1937 Hulusi Behqet described the syndrome that bears his name' but the term 'BehNet's disease' is now used in preference to 'Behqet's syndrome'. Behqet, himself, recognized the problems related to its diagnosis for which there remains no diagnostic test. BD is ra...

Evolution on the immunopathology of Chagas disease.

B Cell Antigen Presentation Promotes Th2 Responses and Immunopathology during Chronic Allergic Lung Disease

BACKGROUND The role of B cells in allergic asthma remains undefined. One mechanism by which B cells clearly contribute to allergic disease is via the production of specific immunoglobulin, and especially IgE. Cognate interactions with specific T cells result in T cell help for B cells, resulting in differentiation and immunoglobulin secretion. Proximal to (and required for) T cell-dependent imm...